Wesli, whose real name is Wesley Louissaint, was born in Port-au-Prince, the Haitian capital. Starting in early childhood, he grew up in a world where music was an escape from misery, and he began building his own instruments with whatever materials were at hand. He also sang in the gospel choir of a local church.
He ended up choosing the guitar as his instrument and became involved with groups such as the Afro-roots jazz quartet 4ever as well as SoKute. While performing on many stages in Haiti, he went off to give concerts abroad with the group Kreyol Mizik. With SoKute, he recorded the album Horizon, which earned the group great success in their country and the beginnings of international recognition.
In 2001, Wesli came to live in Montréal. He worked at various festivals (Nuits d’Afrique, Les Francofolies and the Montréal International Jazz Festival) and also performed regularly with his group on many stages in Canada. He also performed as a guitarist for recognized names in Caribbean music as well as for various Montréal artists (Lorraine Klaasen, Lilison Di Kinara, Gage, Inword and Nathalie Choquette) and also for African artists visiting Montréal (Sekouba Bambino and Monique Seka). With his group, he provided the opening act for Tiken Jah Fakoly and Magic System at the Olympia de Montréal and for Alpha Blondy at the Metropolis.
His first solo album, Kouraj, was acclaimed by critics and the public in 2009. It would be followed by Liberté dans le noir in late 2011 and then by two more albums in 2015, Immigrand and Ayiti étoile nouvelle.